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Myoglobin-catalyzed intermolecular carbene N-H insertion with arylamine substrates

Engineered variants of the heme-containing protein myoglobin can efficiently catalyze the insertion of α-diazo esters into the N—H bond of arylamines, featuring a combination of high chemoselectivity, elevated turnover numbers, and broad substrate scope.

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Bibliografski detalji
Izdano u:Chem Commun (Camb)
Glavni autori: Sreenilayam, Gopeekrishnan, Fasan, Rudi
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282819/
https://ncbi.nlm.nih.gov/pubmed/25504318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc08753d
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