D-AKAP2:PKA RII:PDZK1 ternary complex structure: Insights from the nucleation of a polyvalent scaffold

A-kinase anchoring proteins (AKAPs) regulate cAMP-dependent protein kinase (PKA) signaling in space and time. Dual-specific AKAP2 (D-AKAP2/AKAP10) binds with high affinity to both RI and RII regulatory subunits of PKA and is anchored to transporters through PDZ domain proteins. Here, we describe a s...

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Bibliografski detalji
Izdano u:Protein Sci
Glavni autori: Sarma, Ganapathy N, Moody, Issa S, Ilouz, Ronit, Phan, Ryan H, Sankaran, Banumathi, Hall, Randy A, Taylor, Susan S
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2015
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282416/
https://ncbi.nlm.nih.gov/pubmed/25348485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2593
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