X Chromosome Reactivation Dynamics Reveal Stages of Reprogramming to Pluripotency

Reprogramming to iPSCs resets the epigenome of somatic cells, including the reversal of X chromosome inactivation. We sought to gain insight into the steps underlying the reprogramming process by examining the means by which reprogramming leads to X chromosome reactivation (XCR). Analyzing single ce...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Pasque, Vincent, Tchieu, Jason, Karnik, Rahul, Uyeda, Molly, Dimashkie, Anupama Sadhu, Case, Dana, Papp, Bernadett, Bonora, Giancarlo, Patel, Sanjeet, Ho, Ritchie, Schmidt, Ryan, McKee, Robin, Sado, Takashi, Tada, Takashi, Meissner, Alexander, Plath, Kathrin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282187/
https://ncbi.nlm.nih.gov/pubmed/25525883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.040
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