Ligation of TLR7 by rheumatoid arthritis synovial fluid single strand RNA induces transcription of TNF-α in monocytes

OBJECTIVE: The aim of the study was to characterize the expression, regulation and pathogenic role of TLR7 and TLR8 in rheumatoid arthritis (RA). METHODS: Expression of TLR7 and TLR8 was demonstrated in RA, osteoarthritis (OA) and normal (NL) synovial tissues (ST) employing immunohistochemistry. We...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Ann Rheum Dis
Autori principali: Chamberlain, Nathan D., Kim, Seung-jae, Vila, Olga M., Volin, Michael V., Volkov, Suncica, Pope, Richard M., Arami, Shiva, Mandelin, Arthur M., Shahrara, Shiva
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281889/
https://ncbi.nlm.nih.gov/pubmed/22730373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-201203
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi