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TLR5; a novel and unidentified inflammatory mediator in Rheumatoid Arthritis that correlates with disease activity score and joint TNF-α levels

The innate immune system plays an important role in rheumatoid arthritis (RA) pathogenesis. Previous studies support the role of TLR2 and 4 in RA and experimental arthritis models however the regulation and pathogenic effect of TLR5 is undefined in RA. In this study we show that TLR5 is elevated in...

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Autors principals: Chamberlain, Nathan D., Vila, Olga M., Volin, Michael V., Volkov, Suncica, Pope, Richard M., Swedler, William, Mandelin, Arthur M., Shahrara, Shiva
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614068/
https://ncbi.nlm.nih.gov/pubmed/22661088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102977
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