Identification of a Novel Toll-like Receptor 7 Endogenous Ligand in Rheumatoid Arthritis Synovial Fluid That Can Provoke Arthritic Joint Inflammation

OBJECTIVE: Levels of Toll-like receptor 7 (TLR-7) are elevated in rheumatoid arthritis (RA), but the impact on RA is unknown because the endogenous ligand for TLR-7 has not been identified. The aim of this study was to identify a TLR-7 endogenous ligand and to determine its role in the pathogenesis...

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Publicado no:Arthritis Rheumatol
Main Authors: Kim, Seung-jae, Chen, Zhenlong, Essani, Abdul B., Elshabrawy, Hatem A., Volin, Michael V., Volkov, Suncica, Swedler, William, Arami, Shiva, Sweiss, Nadera, Shahrara, Shiva
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221504/
https://ncbi.nlm.nih.gov/pubmed/26662519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39544
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