Interleukin-1β Enhances FasL-Induced Caspase-3/-7 Activity without Increasing Apoptosis in Primary Mouse Hepatocytes

Sustained inflammation may increase the susceptibility of hepatocytes to apoptotic cell death and therefore exacerbate liver damage. Here we report that the pro-inflammatory cytokine IL-1β sensitizes primary murine hepatocytes to Fas ligand (FasL)-induced caspase-3/-7 activity. This process was depe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lutz, Anna, Sanwald, Julia, Thomas, Maria, Feuer, Ronny, Sawodny, Oliver, Ederer, Michael, Borner, Christoph, Humar, Matjaz, Merfort, Irmgard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281199/
https://ncbi.nlm.nih.gov/pubmed/25551609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115603
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados