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Modeling the TNFα-Induced Apoptosis Pathway in Hepatocytes

The proinflammatory cytokine TNFα fails to provoke cell death in isolated hepatocytes but has been implicated in hepatocyte apoptosis during liver diseases associated with chronic inflammation. Recently, we showed that TNFα is able to sensitize primary murine hepatocytes cultured on collagen to Fas...

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Detalhes bibliográficos
Main Authors: Schlatter, Rebekka, Schmich, Kathrin, Lutz, Anna, Trefzger, Judith, Sawodny, Oliver, Ederer, Michael, Merfort, Irmgard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080376/
https://ncbi.nlm.nih.gov/pubmed/21533085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018646
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