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Hot Fusion: An Efficient Method to Clone Multiple DNA Fragments as Well as Inverted Repeats without Ligase

Molecular cloning is utilized in nearly every facet of biological and medical research. We have developed a method, termed Hot Fusion, to efficiently clone one or multiple DNA fragments into plasmid vectors without the use of ligase. The method is directional, produces seamless junctions and is not...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Fu, Changlin, Donovan, William P., Shikapwashya-Hasser, Olga, Ye, Xudong, Cole, Robert H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281135/
https://ncbi.nlm.nih.gov/pubmed/25551825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115318
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