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Recombination-restarted replication makes inverted chromosome fusions at inverted repeats

Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCR) and copy number variations (CNV). GCRs/CNVs underlie human genomic disorders(1) and are a feature of cancer(2). During cancer development environmental factors and oncogene-driven proliferation promote replicat...

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書誌詳細
主要な著者: Mizuno, Ken’Ichi, Miyabe, Izumi, Schalbetter, Stephanie, Carr, Antony M., Murray, Johanne M.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605775/
https://ncbi.nlm.nih.gov/pubmed/23178809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11676
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