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Recombination-restarted replication makes inverted chromosome fusions at inverted repeats
Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCR) and copy number variations (CNV). GCRs/CNVs underlie human genomic disorders(1) and are a feature of cancer(2). During cancer development environmental factors and oncogene-driven proliferation promote replicat...
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| Hoofdauteurs: | , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605775/ https://ncbi.nlm.nih.gov/pubmed/23178809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11676 |
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