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Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements

Replication fork inactivation can be overcome by homologous recombination, but this can cause gross chromosomal rearrangements that subsequently missegregate at mitosis, driving further chromosome instability. It is unclear when the chromosome rearrangements are generated and whether individual repl...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Mohebi, Saed, Mizuno, Ken’Ichi, Watson, Adam, Carr, Antony M., Murray, Johanne M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351560/
https://ncbi.nlm.nih.gov/pubmed/25721418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7357
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