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Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements
Replication fork inactivation can be overcome by homologous recombination, but this can cause gross chromosomal rearrangements that subsequently missegregate at mitosis, driving further chromosome instability. It is unclear when the chromosome rearrangements are generated and whether individual repl...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Pub. Group
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351560/ https://ncbi.nlm.nih.gov/pubmed/25721418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7357 |
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