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Short Inverted Repeats Are Hot Spots For Genetic Instability: Relevance to Cancer Genomes
Analyses of chromosomal aberrations in human genetic disorders have revealed that inverted repeat sequences (IRs) often co-localize with endogenous chromosomal instability and breakage hotspots. Approximately 80% of all IRs in the human genome are short (<100 bp), yet the mutagenic potential of s...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013304/ https://ncbi.nlm.nih.gov/pubmed/25772355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.039 |
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