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Methods to determine DNA structural alterations and genetic instability

Chromosomal DNA is a dynamic structure that can adopt a variety of non-canonical (i.e. non-B) conformations. In this regard, at least ten different forms of non-B DNA conformations have been identified, and many of them have been found to be mutagenic, and associated with human disease development....

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Autori principali: Wang, Guliang, Zhao, Junhua, Vasquez, Karen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693251/
https://ncbi.nlm.nih.gov/pubmed/19245837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.02.012
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