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Methods to detect replication-dependent and replication-independent DNA structure-induced genetic instability

DNA can adopt a variety of alternative secondary (i.e., non-B DNA) conformations that play important roles in cellular metabolism, including genetic instability, disease etiology, and evolution. While we still have much to learn, research in this field has expanded dramatically in the past decade. W...

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Bibliographic Details
Main Authors: Wang, Guliang, Gaddis, Sally, Vasquez, Karen M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842213/
https://ncbi.nlm.nih.gov/pubmed/23954565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.08.004
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