RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD

Nonsense-mediated mRNA decay (NMD) is a conserved RNA decay pathway that degrades aberrant mRNAs and directly regulates many normal mRNAs. This dual role for NMD raises the possibility that its magnitude is buffered to prevent the potentially catastrophic alterations in gene expression that would ot...

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Publicado en:Mol Cell
Main Authors: Huang, Lulu, Lou, Chih-Hong, Chan, Waikin, Shum, Eleen Y., Shao, Ada, Stone, Erica, Karam, Rachid, Song, Hye-Won, Wilkinson, Miles F.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281029/
https://ncbi.nlm.nih.gov/pubmed/21925383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.031
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