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A conserved microRNA/NMD regulatory circuit controls gene expression

Nonsense-mediated decay (NMD) is a RNA surveillance pathway that degrades subsets of normal and aberrant mRNAs. Mutations that perturb NMD cause neurological disorders in humans, suggesting that NMD has roles in the brain. Recently, it was shown that NMD is repressed during neural development to all...

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Detalhes bibliográficos
Main Authors: Karam, Rachid, Wilkinson, Miles
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342942/
https://ncbi.nlm.nih.gov/pubmed/22258150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.9.1.18010
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