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RNA degradation drives stem cell differentiation

The mechanisms by which multi-potent stem cells switch their program to become functional differentiated cells have intrigued biologists for decades. Most focus has been on transcriptional pathways, but whether they have sufficient dynamic range to cause discrete shifts in cell state is not clear. B...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Lou, Chih-Hong, Shum, Eleen Y, Wilkinson, Miles F
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475395/
https://ncbi.nlm.nih.gov/pubmed/25899816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591631
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