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RNA degradation drives stem cell differentiation

The mechanisms by which multi-potent stem cells switch their program to become functional differentiated cells have intrigued biologists for decades. Most focus has been on transcriptional pathways, but whether they have sufficient dynamic range to cause discrete shifts in cell state is not clear. B...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Lou, Chih-Hong, Shum, Eleen Y, Wilkinson, Miles F
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475395/
https://ncbi.nlm.nih.gov/pubmed/25899816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591631
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