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RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD
Nonsense-mediated mRNA decay (NMD) is a conserved RNA decay pathway that degrades aberrant mRNAs and directly regulates many normal mRNAs. This dual role for NMD raises the possibility that its magnitude is buffered to prevent the potentially catastrophic alterations in gene expression that would ot...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281029/ https://ncbi.nlm.nih.gov/pubmed/21925383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.031 |
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