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The Role of the Hypoxia Response in Shaping Retinal Vascular Development in the Absence of Norrin/Frizzled4 Signaling

PURPOSE. To define the role of hypoxia and vascular endothelial growth factor (VEGF) in modifying the pattern, density, and permeability of the retinal vasculature in mouse models in which Norrin/Frizzled4 signaling is impaired. METHODS. Retinal vascular structure was analyzed in mice with mutation...

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Xehetasun bibliografikoak
Argitaratua izan da:Invest Ophthalmol Vis Sci
Egile Nagusiak: Rattner, Amir, Wang, Yanshu, Zhou, Yulian, Williams, John, Nathans, Jeremy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Association for Research in Vision and Ophthalmology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280883/
https://ncbi.nlm.nih.gov/pubmed/25414188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15693
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