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The Role of the Hypoxia Response in Shaping Retinal Vascular Development in the Absence of Norrin/Frizzled4 Signaling
PURPOSE. To define the role of hypoxia and vascular endothelial growth factor (VEGF) in modifying the pattern, density, and permeability of the retinal vasculature in mouse models in which Norrin/Frizzled4 signaling is impaired. METHODS. Retinal vascular structure was analyzed in mice with mutation...
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| Pubblicato in: | Invest Ophthalmol Vis Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Association for Research in Vision and Ophthalmology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280883/ https://ncbi.nlm.nih.gov/pubmed/25414188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15693 |
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