Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction

Recent studies suggest that peroxisome proliferator-activated receptor gamma (PPARγ) agonists may have cancer chemopreventive activity. Other studies have shown that loss of epidermal PPARγ results in enhanced chemical carcinogenesis in mice via unknown mechanisms. However, ultraviolet B (UVB) expos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Cancer
Egile Nagusiak: Sahu, Ravi P., DaSilva, Sonia C., Rashid, Badri, Martel, Kellie Clay, Jernigan, Danielle, Mehta, Shama R., Mohamed, Deena R., Rezania, Samin, Bradish, Joshua R., Armstrong, Andrew B., Warren, Simon, Konger, Raymond L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280796/
https://ncbi.nlm.nih.gov/pubmed/22467332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27562
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