Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction

Recent studies suggest that peroxisome proliferator-activated receptor gamma (PPARγ) agonists may have cancer chemopreventive activity. Other studies have shown that loss of epidermal PPARγ results in enhanced chemical carcinogenesis in mice via unknown mechanisms. However, ultraviolet B (UVB) expos...

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Библиографические подробности
Опубликовано в: :Int J Cancer
Главные авторы: Sahu, Ravi P., DaSilva, Sonia C., Rashid, Badri, Martel, Kellie Clay, Jernigan, Danielle, Mehta, Shama R., Mohamed, Deena R., Rezania, Samin, Bradish, Joshua R., Armstrong, Andrew B., Warren, Simon, Konger, Raymond L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280796/
https://ncbi.nlm.nih.gov/pubmed/22467332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27562
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