Topical Application of a Platelet Activating Factor Receptor Agonist Suppresses Phorbol Ester-Induced Acute and Chronic Inflammation and Has Cancer Chemopreventive Activity in Mouse Skin

Platelet activating factor (PAF) has long been associated with acute edema and inflammatory responses. PAF acts by binding to a specific G-protein coupled receptor (PAF-R, Ptafr). However, the role of chronic PAF-R activation on sustained inflammatory responses has been largely ignored. We recently...

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Bibliographic Details
Published in:PLoS One
Main Authors: Sahu, Ravi P., Rezania, Samin, Ocana, Jesus A., DaSilva-Arnold, Sonia C., Bradish, Joshua R., Richey, Justin D., Warren, Simon J., Rashid, Badri, Travers, Jeffrey B., Konger, Raymond L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222871/
https://ncbi.nlm.nih.gov/pubmed/25375862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111608
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