Topical Application of a Platelet Activating Factor Receptor Agonist Suppresses Phorbol Ester-Induced Acute and Chronic Inflammation and Has Cancer Chemopreventive Activity in Mouse Skin

Platelet activating factor (PAF) has long been associated with acute edema and inflammatory responses. PAF acts by binding to a specific G-protein coupled receptor (PAF-R, Ptafr). However, the role of chronic PAF-R activation on sustained inflammatory responses has been largely ignored. We recently...

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Udgivet i:PLoS One
Main Authors: Sahu, Ravi P., Rezania, Samin, Ocana, Jesus A., DaSilva-Arnold, Sonia C., Bradish, Joshua R., Richey, Justin D., Warren, Simon J., Rashid, Badri, Travers, Jeffrey B., Konger, Raymond L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222871/
https://ncbi.nlm.nih.gov/pubmed/25375862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111608
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