Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways

Reactive oxygen species (ROS) participate in the pathogenesis of emphysema. Among ROS-producing enzymes, NOX NADPH oxidases are thought to be responsible for tissue injury associated with several lung pathologies. To determine whether NOX2 and/or NOX1 participate in the development of emphysema, the...

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Bibliografski detalji
Izdano u:J Pathol
Glavni autori: Trocme, Candice, Deffert, Christine, Cachat, Julien, Donati, Yves, Tissot, Christelle, Papacatzis, Sylvie, Braunersreuther, Vincent, Pache, Jean-Claude, Krause, Karl-Heinz, Holmdahl, Rikard, Barazzone-Argiroffo, Constance, Carnesecchi, Stéphanie
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Original Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280678/
https://ncbi.nlm.nih.gov/pubmed/25116588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4423
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