Prevention of hyperoxia-induced bronchial hyperreactivity by sildenafil and vasoactive intestinal peptide: impact of preserved lung function and structure

OBJECTIVE: Hyperoxia exposure leads to the development of lung injury and bronchial hyperreactivity (BHR) via involvement of nitric oxide (NO) pathway. We aimed at characterizing whether the stimulation of the NO pathway by sildenafil or vasoactive intestinal peptide (VIP) is able to prevent the hyp...

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Vydáno v:Respir Res
Hlavní autoři: Czövek, Dorottya, Peták, Ferenc, Donati, Yves, Belin, Xavier, Pache, Jean-Claude, Barazzone Argiroffo, Constance, Habre, Walid
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261898/
https://ncbi.nlm.nih.gov/pubmed/25117627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-15-81
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