Prevention of hyperoxia-induced bronchial hyperreactivity by sildenafil and vasoactive intestinal peptide: impact of preserved lung function and structure

OBJECTIVE: Hyperoxia exposure leads to the development of lung injury and bronchial hyperreactivity (BHR) via involvement of nitric oxide (NO) pathway. We aimed at characterizing whether the stimulation of the NO pathway by sildenafil or vasoactive intestinal peptide (VIP) is able to prevent the hyp...

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Publicado en:Respir Res
Main Authors: Czövek, Dorottya, Peták, Ferenc, Donati, Yves, Belin, Xavier, Pache, Jean-Claude, Barazzone Argiroffo, Constance, Habre, Walid
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261898/
https://ncbi.nlm.nih.gov/pubmed/25117627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-15-81
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