NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome

Reactive oxygen species (ROS) contribute to alveolar cell death in Acute Respiratory Distress Syndrome (ARDS) and we previously demonstrated that NOX1-derived ROS contributed to hyperoxia-induced alveolar cell death in mice. The study investigates whether NOX1 expression is modulated in epithelial c...

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Hauptverfasser: Carnesecchi, Stephanie, Dunand-Sauthier, Isabelle, Zanetti, Filippo, Singovski, Grigory, Deffert, Christine, Donati, Yves, Cagarelli, Thomas, Pache, Jean-Claude, Krause, Karl-Heinz, Reith, Walter, Barazzone-Argiroffo, Constance
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925898/
https://ncbi.nlm.nih.gov/pubmed/24551274
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