A Key Role for NOX4 in Epithelial Cell Death During Development of Lung Fibrosis

The pathogenesis of pulmonary fibrosis is linked to oxidative stress, possibly generated by the reactive oxygen species (ROS) generating NADPH oxidase NOX4. Epithelial cell death is a crucial early step in the development of the disease, followed only later by the fibrotic stage. We demonstrate that...

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Detalhes bibliográficos
Main Authors: Carnesecchi, Stephanie, Deffert, Christine, Donati, Yves, Basset, Olivier, Hinz, Boris, Preynat-Seauve, Olivier, Guichard, Cecile, Arbiser, Jack L., Banfi, Botond, Pache, Jean-Claude, Barazzone-Argiroffo, Constance, Krause, Karl-Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163392/
https://ncbi.nlm.nih.gov/pubmed/21391892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3829
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