A Key Role for NOX4 in Epithelial Cell Death During Development of Lung Fibrosis

The pathogenesis of pulmonary fibrosis is linked to oxidative stress, possibly generated by the reactive oxygen species (ROS) generating NADPH oxidase NOX4. Epithelial cell death is a crucial early step in the development of the disease, followed only later by the fibrotic stage. We demonstrate that...

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Main Authors: Carnesecchi, Stephanie, Deffert, Christine, Donati, Yves, Basset, Olivier, Hinz, Boris, Preynat-Seauve, Olivier, Guichard, Cecile, Arbiser, Jack L., Banfi, Botond, Pache, Jean-Claude, Barazzone-Argiroffo, Constance, Krause, Karl-Heinz
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2011
Fag:
Original Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163392/
https://ncbi.nlm.nih.gov/pubmed/21391892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3829
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