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Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo
Malaria remains a major global health problem. Emerging resistance to existing antimalarial drugs drives the search for new antimalarials, and protein translation is a promising pathway to target. Here we explore the potential of the aminoacyl-tRNA synthetase (ARS) family as a source of antimalarial...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280603/ https://ncbi.nlm.nih.gov/pubmed/25489076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405994111 |
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