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The growing pipeline of natural aminoacyl-tRNA synthetase inhibitors for malaria treatment

Malaria remains a major global health problem. Parasite resistance to existing drugs makes development of new antimalarials an urgency. The protein synthesis machinery is an excellent target for the development of new anti-infectives, and aminoacyl-tRNA synthetases (aaRS) have been validated as anti...

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Bibliografiske detaljer
Udgivet i:Bioengineered
Main Authors: Saint-Léger, Adélaïde, Sinadinos, Christopher, Ribas de Pouplana, Lluís
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879988/
https://ncbi.nlm.nih.gov/pubmed/26963157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1149270
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