An Appended Domain Results in an Unusual Architecture for Malaria Parasite Tryptophanyl-tRNA Synthetase

Specific activation of amino acids by aminoacyl-tRNA synthetases (aaRSs) is essential for maintaining fidelity during protein translation. Here, we present crystal structure of malaria parasite Plasmodium falciparum tryptophanyl-tRNA synthetase (Pf-WRS) catalytic domain (AAD) at 2.6 Å resolution in...

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Detalhes bibliográficos
Main Authors: Khan, Sameena, Garg, Ankur, Sharma, Arvind, Camacho, Noelia, Picchioni, Daria, Saint-Léger, Adélaïde, de Pouplana, Lluís Ribas, Yogavel, Manickam, Sharma, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680381/
https://ncbi.nlm.nih.gov/pubmed/23776638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066224
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