Llwytho...
Targeting acidity in diseased tissues: mechanism and applications of the membrane-inserting peptide, pHLIP
pHLIPs are a family of soluble ~36 amino acid peptides, which bind to membrane surfaces. If the environment is acidic, a pHLIP folds and inserts across the membrane to form a stable transmembrane helix, thus preferentially locating itself in acidic tissues. Since tumors and other disease tissues are...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Arch Biochem Biophys |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280328/ https://ncbi.nlm.nih.gov/pubmed/25444855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.11.002 |
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