Covariate Imbalance and Adjustment for Logistic Regression Analysis of Clinical Trial Data

In logistic regression analysis for binary clinical trial data, adjusted treatment effect estimates are often not equivalent to unadjusted estimates in the presence of influential covariates. This paper uses simulation to quantify the benefit of covariate adjustment in logistic regression. However,...

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Veröffentlicht in:J Biopharm Stat
Hauptverfasser: Ciolino, Jody D., Martin, Reneé H., Zhao, Wenle, Jauch, Edward C., Hill, Michael D., Palesch, Yuko Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279871/
https://ncbi.nlm.nih.gov/pubmed/24138438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2013.834912
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