Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/β-Catenin Signaling

Activation of the renin-angiotensin system (RAS) plays an essential role in the pathogenesis of CKD and cardiovascular disease. However, current anti-RAS therapy only has limited efficacy, partly because of compensatory upregulation of renin expression. Therefore, a treatment strategy to simultaneou...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Zhou, Lili, Li, Yingjian, Hao, Sha, Zhou, Dong, Tan, Roderick J., Nie, Jing, Hou, Fan Fan, Kahn, Michael, Liu, Youhua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2015
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279741/
https://ncbi.nlm.nih.gov/pubmed/25012166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014010085
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