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Sustained Activation of Wnt/β-Catenin Signaling Drives AKI to CKD Progression

AKI is increasingly recognized as a major risk factor for progression to CKD. However, the factors governing AKI to CKD progression are poorly understood. In this study, we investigated this issue using moderate (20 minutes) and severe (30 minutes) ischemia/reperfusion injury (IRI) in mice. Moderate...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Xiao, Liangxiang, Zhou, Dong, Tan, Roderick J., Fu, Haiyan, Zhou, Lili, Hou, Fan Fan, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884114/
https://ncbi.nlm.nih.gov/pubmed/26453613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040449
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