Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy

BACKGROUND: Familial restrictive cardiomyopathy (FRCM) has a poor prognosis due to diastolic dysfunction and restrictive physiology (RP). Myocardial stiffness, with or without fibrosis, underlie the RP, but the mechanism(s) of restrictive remodeling is unclear. Myopalladin (MYPN) is a messenger mole...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Coll Cardiol
Main Authors: Huby, Anne-Cecile, Mendsaikhan, Uzmee, Takagi, Ken, Martherus, Ruben, Wansapura, Janaka, Gong, Nan, Osinska, Hanna, James, Jeanne, Kramer, Kristen, Saito, Kazuyoshi, Robbins, Jeffrey, Khuchua, Zaza, Towbin, Jeffrey A., Purevjav, Enkhsaikhan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279060/
https://ncbi.nlm.nih.gov/pubmed/25541130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.09.071
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados