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Capping of Aβ42 Oligomers by Small Molecule Inhibitors

[Image: see text] Aβ42 peptides associate into soluble oligomers and protofibrils in the process of forming the amyloid fibrils associated with Alzheimer’s disease. The oligomers have been reported to be more toxic to neurons than fibrils, and have been targeted by a wide range of small molecule and...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Fu, Ziao, Aucoin, Darryl, Ahmed, Mahiuddin, Ziliox, Martine, Van Nostrand, William E., Smith, Steven O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278677/
https://ncbi.nlm.nih.gov/pubmed/25422864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500910b
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