Epitope spreading as an early pathogenic event in pediatric multiple sclerosis

OBJECTIVES: For most adults with initial clinical presentation of multiple sclerosis (MS), biological disease was likely initiated many years prior. Pediatric-onset MS provides an opportunity to study early disease processes. METHODS: Using antigen microarrays, including CNS-related proteins, lipids...

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Publicado en:Neurology
Autores principales: Quintana, Francisco J., Patel, Bonny, Yeste, Ada, Nyirenda, Mukanthu, Kenison, Jessica, Rahbari, Roya, Fetco, Dumitru, Hussain, Mohammad, O'Mahony, Julia, Magalhaes, Sandra, McGowan, Melissa, Johnson, Trina, Rajasekharan, Sathy, Narayanan, Sridar, Arnold, Douglas L., Weiner, Howard L., Banwell, Brenda, Bar-Or, Amit
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277672/
https://ncbi.nlm.nih.gov/pubmed/25381299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001066
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