Epitope spreading as an early pathogenic event in pediatric multiple sclerosis

OBJECTIVES: For most adults with initial clinical presentation of multiple sclerosis (MS), biological disease was likely initiated many years prior. Pediatric-onset MS provides an opportunity to study early disease processes. METHODS: Using antigen microarrays, including CNS-related proteins, lipids...

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Veröffentlicht in:Neurology
Hauptverfasser: Quintana, Francisco J., Patel, Bonny, Yeste, Ada, Nyirenda, Mukanthu, Kenison, Jessica, Rahbari, Roya, Fetco, Dumitru, Hussain, Mohammad, O'Mahony, Julia, Magalhaes, Sandra, McGowan, Melissa, Johnson, Trina, Rajasekharan, Sathy, Narayanan, Sridar, Arnold, Douglas L., Weiner, Howard L., Banwell, Brenda, Bar-Or, Amit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277672/
https://ncbi.nlm.nih.gov/pubmed/25381299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001066
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