Epitope spreading as an early pathogenic event in pediatric multiple sclerosis

OBJECTIVES: For most adults with initial clinical presentation of multiple sclerosis (MS), biological disease was likely initiated many years prior. Pediatric-onset MS provides an opportunity to study early disease processes. METHODS: Using antigen microarrays, including CNS-related proteins, lipids...

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Gepubliceerd in:Neurology
Hoofdauteurs: Quintana, Francisco J., Patel, Bonny, Yeste, Ada, Nyirenda, Mukanthu, Kenison, Jessica, Rahbari, Roya, Fetco, Dumitru, Hussain, Mohammad, O'Mahony, Julia, Magalhaes, Sandra, McGowan, Melissa, Johnson, Trina, Rajasekharan, Sathy, Narayanan, Sridar, Arnold, Douglas L., Weiner, Howard L., Banwell, Brenda, Bar-Or, Amit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Lippincott Williams & Wilkins 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277672/
https://ncbi.nlm.nih.gov/pubmed/25381299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001066
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