Epitope spreading as an early pathogenic event in pediatric multiple sclerosis

OBJECTIVES: For most adults with initial clinical presentation of multiple sclerosis (MS), biological disease was likely initiated many years prior. Pediatric-onset MS provides an opportunity to study early disease processes. METHODS: Using antigen microarrays, including CNS-related proteins, lipids...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Quintana, Francisco J., Patel, Bonny, Yeste, Ada, Nyirenda, Mukanthu, Kenison, Jessica, Rahbari, Roya, Fetco, Dumitru, Hussain, Mohammad, O'Mahony, Julia, Magalhaes, Sandra, McGowan, Melissa, Johnson, Trina, Rajasekharan, Sathy, Narayanan, Sridar, Arnold, Douglas L., Weiner, Howard L., Banwell, Brenda, Bar-Or, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277672/
https://ncbi.nlm.nih.gov/pubmed/25381299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001066
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