Epitope spreading as an early pathogenic event in pediatric multiple sclerosis

OBJECTIVES: For most adults with initial clinical presentation of multiple sclerosis (MS), biological disease was likely initiated many years prior. Pediatric-onset MS provides an opportunity to study early disease processes. METHODS: Using antigen microarrays, including CNS-related proteins, lipids...

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Vydáno v:Neurology
Hlavní autoři: Quintana, Francisco J., Patel, Bonny, Yeste, Ada, Nyirenda, Mukanthu, Kenison, Jessica, Rahbari, Roya, Fetco, Dumitru, Hussain, Mohammad, O'Mahony, Julia, Magalhaes, Sandra, McGowan, Melissa, Johnson, Trina, Rajasekharan, Sathy, Narayanan, Sridar, Arnold, Douglas L., Weiner, Howard L., Banwell, Brenda, Bar-Or, Amit
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277672/
https://ncbi.nlm.nih.gov/pubmed/25381299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001066
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