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Hand2 is an Essential Regulator for Two Notch-Dependent Functions within the Embryonic Endocardium

The bHLH transcription factor Hand2 plays critical roles during cardiac morphogenesis via expression and function within myocardial, neural crest, and epicardial cell populations. Here we show that Hand2 plays two essential Notch-dependent roles within the endocardium. Endocardial ablation of Hand2...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: VanDusen, Nathan J., Casanovas, Jose, Vincentz, Joshua W., Firulli, Beth A., Osterwalder, Marco, Lopez-Rios, Javier, Zeller, Rolf, Zhou, Bin, Grego-Bessa, Joaquim, De La Pompa, José Luis, Shou, Weinian, Firulli, Anthony B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277501/
https://ncbi.nlm.nih.gov/pubmed/25497097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.021
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