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Hand2 loss-of-function in Hand1-expressing Cells Reveals Distinct Roles In Epicardial And Coronary Vessel Development

RATIONALE: The bHLH transcription factors Hand1 and Hand2 are essential for embryonic development. Given their requirement for cardiogenesis, it is imperative to determine their impact on cardiovascular function. OBJECTIVE: Deduce the role of Hand2 within the epicardium. METHOD & RESULTS: We eng...

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Detalhes bibliográficos
Main Authors: Barnes, Ralston M., Firulli, Beth A., VanDusen, Nathan J., Morikawa, Yuka, Conway, Simon J., Cserjesi, Peter, Vincentz, Joshua W., Firulli, Anthony B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086599/
https://ncbi.nlm.nih.gov/pubmed/21350214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.233171
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