A Phox2- and Hand2-Dependent Hand1 cis-Regulatory Element Reveals a Unique Gene Dosage Requirement for Hand2 during Sympathetic Neurogenesis

Neural crest cell specification and differentiation to a sympathetic neuronal fate serves as an important model for neurogenesis and depends upon the function of both bHLH transcription factors, notably Hand2, and homeodomain transcription factors, including Phox2b. Here, we define a 1007 bp cis-reg...

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Detalhes bibliográficos
Main Authors: Vincentz, Joshua W., VanDusen, Nathan J., Fleming, Andrew B., Rubart, Michael, Firulli, Beth A., Howard, Marthe J., Firulli, Anthony B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324095/
https://ncbi.nlm.nih.gov/pubmed/22323723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3584-11.2012
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