A Phox2- and Hand2-Dependent Hand1 cis-Regulatory Element Reveals a Unique Gene Dosage Requirement for Hand2 during Sympathetic Neurogenesis

Neural crest cell specification and differentiation to a sympathetic neuronal fate serves as an important model for neurogenesis and depends upon the function of both bHLH transcription factors, notably Hand2, and homeodomain transcription factors, including Phox2b. Here, we define a 1007 bp cis-reg...

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Huvudupphovsmän: Vincentz, Joshua W., VanDusen, Nathan J., Fleming, Andrew B., Rubart, Michael, Firulli, Beth A., Howard, Marthe J., Firulli, Anthony B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324095/
https://ncbi.nlm.nih.gov/pubmed/22323723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3584-11.2012
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