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Alpharetroviral Vectors: From a Cancer-Causing Agent to a Useful Tool for Human Gene Therapy

Gene therapy using integrating retroviral vectors has proven its effectiveness in several clinical trials for the treatment of inherited diseases and cancer. However, vector-mediated adverse events related to insertional mutagenesis were also observed, emphasizing the need for safer therapeutic vect...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Suerth, Julia D., Labenski, Verena, Schambach, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276931/
https://ncbi.nlm.nih.gov/pubmed/25490763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6124811
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