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Genome-Wide Analysis of Alpharetroviral Integration in Human Hematopoietic Stem/Progenitor Cells

Gene transfer vectors derived from gamma-retroviruses or lentiviruses are currently used for the gene therapy of genetic or acquired diseases. Retroviral vectors display a non-random integration pattern in the human genome, targeting either regulatory regions (gamma-retroviruses) or the transcribed...

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Hlavní autoři: Moiani, Arianna, Suerth, Julia Debora, Gandolfi, Francesco, Rizzi, Ermanno, Severgnini, Marco, De Bellis, Gianluca, Schambach, Axel, Mavilio, Fulvio
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094940/
https://ncbi.nlm.nih.gov/pubmed/24840152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5020415
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