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Self-Inactivating Alpharetroviral Vectors with a Split-Packaging Design
Accidental insertional activation of proto-oncogenes and potential vector mobilization pose serious challenges for human gene therapy using retroviral vectors. Comparative analyses of integration sites of different retroviral vectors have elucidated distinct target site preferences, highlighting vec...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903275/ https://ncbi.nlm.nih.gov/pubmed/20410274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00182-10 |
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