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Self-Inactivating Alpharetroviral Vectors with a Split-Packaging Design

Accidental insertional activation of proto-oncogenes and potential vector mobilization pose serious challenges for human gene therapy using retroviral vectors. Comparative analyses of integration sites of different retroviral vectors have elucidated distinct target site preferences, highlighting vec...

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Hlavní autoři: Suerth, Julia D., Maetzig, Tobias, Galla, Melanie, Baum, Christopher, Schambach, Axel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903275/
https://ncbi.nlm.nih.gov/pubmed/20410274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00182-10
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