Llwytho...
Adaptor Protein GRB2 Promotes Src Tyrosine Kinase Activation and Podosomal Organization by Protein-tyrosine Phosphatase ϵ in Osteoclasts
The non-receptor isoform of protein-tyrosine phosphatase ϵ (cyt-PTPe) supports adhesion of bone-resorbing osteoclasts by activating Src downstream of integrins. Loss of cyt-PTPe reduces Src activity in osteoclasts, reduces resorption of mineralized matrix both in vivo and in cell culture, and induce...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Biol Chem |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Biochemistry and Molecular Biology
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276870/ https://ncbi.nlm.nih.gov/pubmed/25381250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603548 |
| Tagiau: |
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