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Activation of Src Kinase by Protein–Tyrosine Phosphatase–PEST in Osteoclasts: Comparative Analysis of the Effects of Bisphosphonate and Protein–Tyrosine Phosphatase Inhibitor on Src Activation In Vitro
PTP–PEST is involved in the regulation of sealing ring formation in osteoclasts. In this article, we have shown a regulatory role for PTP–PEST on dephosphorylation of c-Src at Y527 and phosphorylation at Y418 in the catalytic site. Activation of Src in osteoclasts by over-expression of PTP–PEST resu...
Tallennettuna:
| Julkaisussa: | J Cell Physiol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7192836/ https://ncbi.nlm.nih.gov/pubmed/19350555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21777 |
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